Table 2.
Antimicrobial resistance of clinical K. pneumoniae complex isolates from dogs and cats.
| Antimicrobial agents | All isolates (n = 35) | Dog (n = 19) | Cat (n = 16) | p-value‡ | ||||
|---|---|---|---|---|---|---|---|---|
| Resistance, % | MIC50 | MIC90 | Resistance, % | MIC50 | MIC90 | Resistance, % | ||
| Amoxicillin-clavulanate | 29 (82.9) | 32/16 | 64/32 | 14 (73.7) | 64/32 | >256/128 | 15 (93.8) | 0.187 |
| Piperacillin-tazobactam | 14 (40.0) | 4/4 | >256/4 | 5 (26.3) | 32/4 | >256/4 | 9 (56.3) | 0.094 |
| Ceftazidime-avibactam | 1 (2.9) | 0.25/4 | 0.5/4 | 0 | 0.25/4 | 1/4 | 1 (6.3) | 0.457 |
| Cefotaxime | 22 (62.9) | 64 | >256 | 10 (52.6) | 256 | >256 | 12 (75.0) | 0.293 |
| Cefepime | 17 (48.6) | 4 | >256 | 9 (47.4) | 8 | 256 | 8 (50.0) | 1.000 |
| Meropenem | 1 (2.9) | 0.06 | 0.125 | 0 | 0.06 | 0.125 | 1 (6.3) | 0.457 |
| Imipenem | 1 (2.9) | 0.5 | 1 | 0 | 0.5 | 1 | 1 (6.3) | 0.457 |
| Aztreonam | 20 (57.1) | 4 | >256 | 9 (47.4) | 128 | >256 | 11 (68.8) | 0.306 |
| Ciprofloxacin | 22 (62.9) | 2 | 128 | 10 (52.6) | 32 | 256 | 12 (75.0) | 0.293 |
| Enrofloxacin | 21 (60.0) | 1 | 64 | 9 (47.4) | 32 | 64 | 12 (75.0) | 0.166 |
| Gentamicin | 22 (62.9) | 64 | >256 | 11 (57.9) | 64 | >256 | 11 (68.8) | 0.727 |
| Amikacin | 11 (31.4) | 2 | >256 | 4 (21.1) | 8 | >256 | 7 (43.8) | 0.273 |
| Doxycycline | 23 (65.7) | 32 | 64 | 11 (57.9) | 32 | 64 | 12 (75.0) | 0.476 |
| Colistin | 2 (5.7) | 2 | 2 | 0 | 2 | 2 | 2 (12.5) | 0.202 |
| Florfenicol | 23 (65.7) | 256 | >256 | 13 (68.4) | 16 | 256 | 10 (62.5) | 0.736 |
| Trimethoprim-sulfamethoxazole | 27 (77.1) | >32/608 | >32/608 | 14 (73.7) | >32/608 | >32/608 | 13 (81.3) | 0.700 |
‡
p-values were determined by Fisher's exact test in SPSS Statistics.
*p < 0.05.
**p < 0.01.