Table 1.
Meta-analytic epidemiological estimates of age at onset of mental disorder (ICD-11 blocks highlighted in italics) in the general population.
| No of Samples | Peak age at onset (years) | Proportion onset by 14 years | Proportion onset by 18 years | Proportion onset by 25 years | p25 | Median | p75 | |
|---|---|---|---|---|---|---|---|---|
| Any mental disorder | 14 | 14.5 | 34.6% | 48.4% | 62.5% | 11 | 18 | 34 |
| Neurodevelopmental disorders | 21 | 5.5 | 61.5% | 83.2% | 95.8% | 7 | 12 | 16 |
| Autism spectrum disorder | 2 | 5.5 | 72.4% | 89.8% | 94.8% | 5 | 9 | 14 |
| Attention deficit hyperactivity disorder | 12 | 9.5 | 56.8% | 73.0% | 91.8% | 8 | 12 | 18 |
| Anxiety and fear-related disorders | 73 | 5.5 | 38.1% | 51.8% | 73.3% | 9 | 17 | 25 |
| Specific phobia/separation anxiety disorder | 22 | 5.5 | 72.4% | 75.0% | 80.4% | 5 | 8 | 17 |
| Social anxiety disorder | 42 | 14.5 | 50.9% | 79.1% | 87.5% | 9 | 13 | 17 |
| Panic disorder | 22 | 15.5 | 8.2% | 22.5% | 45.7% | 18 | 26 | 36 |
| Generalised anxiety disorder | 24 | 15.5 | 8.6% | 20.4% | 33.0% | 20 | 32 | 42 |
| Obsessive-compulsive related disorders | 20 | 14.5 | 24.6% | 45.1% | 64.0% | 14 | 19 | 29 |
| Obsessive-compulsive disorder | 20 | 14.5 | 24.6% | 45.1% | 64.0% | 14 | 19 | 29 |
| Feeding or eating disorders | 11 | 15.5 | 15.8% | 48.1% | 82.4% | 15 | 18 | 23 |
| Anorexia nervosa | 8 | 15.5 | 18.2% | 55.2% | 78.7% | 14 | 17 | 22 |
| Bulimia Nervosa | 8 | 15.5 | 16.0% | 45.3% | 82.9% | 15 | 18 | 22 |
| Binge eating disorder | 5 | 19.5 | 12.3% | 34.5% | 73.5% | 16 | 20 | 25 |
| Trauma-related disorders | 16 | 15.5 | 16.9% | 27.6% | 43.1% | 17 | 30 | 48 |
| Post-traumatic stress disorder | 16 | 15.5 | 16.9% | 27.6% | 43.1% | 17 | 30 | 48 |
| Disorders due to substance use or addictive behaviours | 58 | 19.5 | 2.9% | 15.2% | 48.8% | 20 | 25 | 41 |
| Disorder due to use of cannabis | 10 | 19.5 | 3.2% | 17.5% | 64.6% | 19 | 22 | 29 |
| Disorder due to use of alcohol | 44 | 19.5 | 4.2% | 18.3% | 44.8% | 19 | 27 | 43 |
| Schizophrenia-spectrum and primary psychotic disorders | 36 | 20.5 | 3.0% | 12.3% | 47.8% | 20 | 25 | 34 |
| Schizophrenia | 25 | 20.5 | 2.0% | 8.2% | 47.4% | 21 | 25 | 35 |
| Acute and transient psychotic disorder | 2 | 18.5 | 1.8% | 6.6% | 20.6% | 27 | 35 | 45 |
| Personality disorders | 6 | 20.5 | 1.9% | 9.6% | 47.7% | 20 | 25 | 33 |
| Mood disorders | 79 | 20.5 | 2.5% | 11.5% | 34.5% | 21 | 31 | 46 |
| Depressive disorders | 62 | 19.5 | 3.1% | 13.2% | 36.9% | 21 | 30 | 44 |
| Bipolar or related disorders | 40 | 19.5 | 5.1% | 13.7% | 32.0% | 22 | 33 | 49 |
p25, p75, 25th and 75th percentile. Only the earliest peaks are shown. Different metric on the same sample has been extracted from multiple studies.