TABLE 3.

Association between RET rs2435357 and risk of HSCR from all samples.

	Rectal + Blood samples		OR (95% CI); p
Genotype	Cases (n,%)	Controls (n,%)	Dominant (TT + CT vs. CC)	Recessive (TT vs. CT + CC)
CC	4	32	7.90 (2.73–22.85); 4.9 × 10–6^*	2.8 × 10–25^*
CT	33	117
TT	129	47
Allele
C	41	209	8.11 (5.53–11.88); 3.7 × 10–32^*
T	291	183

*Significance p < 0.05; CI, confidence interval; HSCR, Hirschsprung disease; OR, odds ratio.