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. 2022 Mar 10;10:846665. doi: 10.3389/fbioe.2022.846665

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Copyright © 2022 Tortorici, Petersen, Duda and Checa.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Model of osteochondral defect repair. (A) Geometry (left) and mesh (right) of the axisymmetric model of knee femoral condyle. Black arrows and the black triangle show the applied pressure and the encastre boundary condition in the finite element (FE) analysis, respectively; (B) workflow of the model. S = mechanics-dependent stimulus of tissue formation.