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. 2022 Mar 10;12:798401. doi: 10.3389/fonc.2022.798401

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Copyright © 2022 Cui, Liu, Wu, Liang, Dai, Zhang and Guo

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Validation of the predictive significance of AHNAK2 in pan-cancer. (A) Lollipop plots showing the locus distribution of mutations across the AHNAK2-altered patient cohorts. (B) Flow diagram of the identification of del-AHNAK2mut and non-del-AHNAK2mut by mutational forms and PROVEAN. (C) Kaplan–Meier curves of PFS in the discovery cohort classified by AHNAK2 mutations. (D) Kaplan–Meier curves of OS in the validation cohort classified by AHNAK2 mutations. (E) Kaplan–Meier curves of PFSS in the validation cohort classified by AHNAK2 mutations. (F) Kaplan–Meier curves of OS in the TCGA cohort classified by AHNAK2 mutations. (G) Kaplan–Meier curves of PFS in the TCGA cohort classified by AHNAK2 mutations.