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. 2022 Mar 28;13:1640. doi: 10.1038/s41467-022-29336-y

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — a Heat-map displays genes mutated in ≥3 AML cases. Cases are separated into FAB groups (columns), and the genes are grouped into six biological pathways (rows). Colors represent mutation types. b Pairwise co-occurrence (red) and mutual exclusive (blue) correlations between driver genes (two-sided Fisher’s exact test). The correlations are labeled with hollow circle if the pairs of mutations/genes were from a same gene or fusion.