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. 2022 Mar 28;12:5283. doi: 10.1038/s41598-022-09261-2

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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(A,B) The gross appearance of a globe with severe microphthalmos. (C) Histopathological appearance of the globe with absent lens and dysgenesis of the anterior chamber angle structures and gliosis of the retina (original magnification × 12.5, hematoxylin and eosin). (D) Higher power of the anterior segment showing absent angle structures with uveal tissue adherent to the back of the cornea and obliterated narrow anterior chamber (original magnification × 100, hematoxylin and eosin).