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. 2022 Mar 28;12:5264. doi: 10.1038/s41598-022-09183-z

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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The morphology of distal rabbit femur one year after implantation. Complete embedding of the screw by the bone is visible (top row). The tissue in the contact with the head is partly cartilaginous (middle row), while the tip is covered by newly-formed bone (bottom row). Van Gieson/orcein staining (top row) and hematoxylin–eosin staining, scale bars 1 mm (top row) and 200 µm (remaining panels). Control = unoperated side.