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. 2022 Mar 19;34:67–74. doi: 10.1016/j.ctro.2022.03.005

Table 1.

Main features of the studies eligible for inclusion with median follow-up time > 5 years.

Author,
Year
Sample size

(Recruitment period)
Tumor
Histology

(WHO type)
Stage

(M−K)
Margin status RT intent
(n)
RT technique
(n)
Median RT Dose in Gy (range) Median Follow-up
months (range)
RECURRENCES of TETs
Yang 2019 [39] 47
(2007–2015)
TETs
(A-B3 + C)
Recurr. n/a dRT
(47)
3D-CRT (29)
IMRT (18)
52 Gy
(30–70)
83
(8–299)
THYMOMA (M−K II)
Chen 2010
[36]
107*
(1964–2006)
Thymoma
(A-B3)
II R0 PORT

(66)
2D-RT (44)
3D-CRT (22)
60 Gy
(22–60)
63
(2–303)

Abbreviations: TETs = thymic epithelial tumors; WHO = World health organization; M−K = Masaoka-Koga surgical tumor stage classification; n/a = not applicable; PORT = Post operative RT; dRT = Radiotherapy alone with definitive or curative intent; 3D-CRT = 3D conformal radiotherapy; IMRT: Intensity modulated radiotherapy; R0 = complete resection; Recurr. = recurrence; n = number of patients.

*The original study sample differs from the patients undergoing RT with modern techniques (e.g. the final sample size used for the synthesis).