Table 3.
List of protein-bound 3D structures complexed with caffeic acid and inferences on binding affinity.
| PDB code | Structure description | Inference |
|---|---|---|
| 1KOU | Photoactive yellow protein complexed with CA | CA binds to the protein in strained conformation, resulting in faster ejection |
| 6I72 | Fragaria ananassa O-methyltransferase and S-adenosylhomocysteine complexed with CA | – |
| 6YRI | HCAII complexed with CA | catechols as inhibitors for CA |
| 4YU7 | Piratoxin I complexed with CA | CA neutralized myotoxic activity of PrTX-I (snake venom) |
| 3S2Z | Lactobacillus johnsonii cinnamoyl esterase LJ0536 S106A mutant in complexed with CA | – |
| 4N0S | ERK2 complexed with CA | Yang et al. (23) suggested CA targets and inhibits ERK1 and 2 for cancer prevention against SUV- induced skin cancer |
| 4FB4 | ABC-transporter family protein complexed with CA | – |
| 2O7D | Tyrosine ammonia-lyase complexed with caffeate | – |
| 3HOF | Macrophage migration inhibitory factor (MIF) complexed with CA | – |
| 4EYQ | ABC transporter HaA2 in complex with CA/3-(4-hydroxy-phenyl) pyruvic acid | – |
| 5VFJ | BnSP-7 complexed with CA | CA as the best inhibitor for MDoS region of BnSP-7 |
| 6AWU | PR 10 Allergen Ara h 8.01 in complex with CA | – |