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Kaplan-Meier Time-to-First Event Curves of DNMT3A or TET2 Separately for Death and MACE. No matter patients with DNMT3A- (a, b) (no-DNMT3A VAF≥2% group, n = 444; DNMT3A VAF≥2% group, n = 41) or TET2- (c,d) (no-TET2 VAF≥2% group, n = 460; TET2 VAF≥2% group, n = 25) CH-driver mutations with a VAF≥2% had higher incidence of death and MACE. P-values are for log-rank tests.
