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. 2022 Mar 10;13:848172. doi: 10.3389/fphys.2022.848172

Table 1.

Principal components analysis.

PC1 PC2 PC3 PC4 PC5 PC6 PC7 PC8
Albumin 0.23 0.08 −0.05 −0.12 −0.06 0.11 −0.17 −0.02
Oxygen saturation 0.24 −0.07 −0.05 −0.1 0 0.08 −0.06 −0.08
PaO2/FiO2 0.22 −0.03 −0.03 −0.04 −0.05 0.02 0.05 −0.04
Estimated glomerular filtration rate 0.15 0.09 −0.13 0.2 0.08 −0.15 0.31 −0.15
Lymphocytes 0.11 0.1 −0.01 0.05 0.02 0.03 −0.13 −0.25
Thoracic subcutaneous a. t. 0.05 0.21 0.27 0.18 −0.02 −0.05 0.05 −0.1
TyG-BMI index −0.08 0.39 0.2 0.05 −0.05 0.12 −0.03 −0.22
Body mass index −0.04 0.4 0.17 0.02 −0.12 −0.01 0 −0.21
Weight −0.03 0.41 0.07 −0.05 −0.21 −0.05 −0.05 −0.1
Hepatic steatosis −0.01 0.23 −0.08 0.09 −0.07 0.13 0.07 0.06
Heart rate −0.06 0.15 −0.2 0.11 0.11 0.03 −0.18 0.19
Axillary temperature 0.01 0.11 −0.09 0 0 −0.04 −0.14 0.15
Prothrombin 0 −0.01 −0.14 −0.08 −0.12 −0.15 −0.22 0.03
Vitamin D 0.03 0.02 −0.14 −0.08 −0.07 −0.03 −0.13 −0.02
Height 0.04 0.11 −0.07 −0.03 −0.19 −0.1 −0.05 0.18
Hemoglobin 0.05 0.1 −0.02 −0.11 −0.09 −0.02 −0.13 −0.08
Diastolic pressure 0.04 0.23 −0.09 −0.24 0.27 −0.03 −0.03 0.09
Mean arterial pressure 0.03 0.25 −0.03 −0.27 0.39 −0.07 0.01 0.15
Systolic pressure 0 0.2 0.07 −0.22 0.44 −0.09 0.05 0.19
Pulse pressure −0.03 0.04 0.14 −0.07 0.29 −0.09 0.09 0.15
Cytopenia 0.02 −0.06 0.13 −0.04 −0.08 0.13 0.03 0.3
Serum creatinine −0.09 −0.04 0.22 −0.01 −0.04 0.18 −0.33 0.17
Consolidation −0.09 0.07 −0.07 0.34 −0.03 −0.22 0.05 0.22
Grounded glass opacity −0.08 0.09 −0.1 0.34 −0.04 −0.22 0.05 0.22
Ventilatory support time −0.11 0.08 −0.07 0.1 −0.06 0.05 −0.15 0.11
Hospitalization time −0.07 0.02 −0.11 0.07 −0.05 0.08 −0.15 0.14
Platelets −0.11 −0.03 −0.17 0.12 0.19 −0.06 0.1 −0.21
Symptomatic time −0.06 0.01 −0.11 −0.1 0.01 −0.1 0.14 −0.14
Indirect bilirubin −0.09 −0.04 −0.09 −0.28 −0.1 −0.15 0.02 −0.17
Direct bilirubin −0.15 −0.01 −0.11 −0.25 −0.15 −0.11 0.05 −0.12
Epicardial fat −0.12 0.06 −0.1 −0.16 −0.14 −0.05 0 0.01
Creatinine kinase −0.06 0.08 −0.03 −0.11 −0.17 0.16 −0.04 0.17
Alanine transaminase −0.07 0.12 −0.19 −0.1 −0.1 0.22 0.35 0.05
Aspartate aminotransferase −0.13 0.04 −0.12 −0.12 −0.17 0.23 0.34 0.13
Ferritin −0.18 0.02 −0.18 −0.2 −0.1 0.12 0.09 0.02
Lactic dehydrogenase −0.24 0.03 −0.09 −0.02 −0.09 0.12 0.11 0.04
Respiratory rate −0.18 0.04 −0.04 0.11 0.07 −0.03 0 0.05
Pulmonary involvement −0.21 0.03 −0.06 0.1 −0.03 −0.14 0.02 −0.03
Fibrinogen −0.2 0 −0.2 0.04 0.13 −0.1 0 −0.12
C-reactive protein −0.22 −0.02 −0.09 −0.01 0.07 −0.07 −0.07 −0.04
Neutrophils/lymphocytes −0.23 −0.09 −0.12 −0.04 0.02 −0.06 −0.11 0.08
Leukocytes −0.21 −0.01 −0.15 0.04 0.09 −0.05 −0.2 −0.16
Total neutrophils −0.15 −0.01 −0.15 0.03 0.07 −0.03 −0.29 −0.18
Triglycerides −0.13 0.04 0 0.13 0.13 0.38 0.04 −0.06
TyG index −0.18 0.04 0.06 0.08 0.16 0.36 −0.02 −0.08
Glucose −0.17 0.02 0.09 −0.02 0.11 0.14 −0.08 −0.03
Blood urea nitrogen −0.21 −0.12 0.16 −0.08 0.02 0.14 −0.18 −0.06
BUN to creatinine ratio −0.14 −0.12 0.15 0.02 0.11 −0.01 0.06 −0.27
D-dimer −0.18 −0.07 0.08 0.02 0 0.02 0.18 0.01
Ultrasensitive troponin −0.15 −0.08 0.25 0.1 0.04 0.01 0.08 0.11
Age −0.12 −0.23 0.26 −0.16 0.04 −0.1 0.08 −0.02
Right pulmonary artery −0.16 0.03 0.21 −0.19 −0.12 −0.23 0.04 0.05
Left pulmonary artery −0.17 0.01 0.21 −0.12 −0.15 −0.2 0.04 0.05
Pulmonary artery trunk −0.12 0.11 0.23 0.03 −0.09 −0.21 −0.04 0.06

Physiological variable contributions to each selected principal component are tabulated according to optimal leaf order.