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. 2022 Mar 10;13:848172. doi: 10.3389/fphys.2022.848172

Table 2.

Physiological variables differences between groups.

Groups compared Summary FYR MYR MYD MOR MOD
Albumin bcd 3.8 ± 0.4 3.8 ± 0.5 3.4 ± 0.4b 3.6 ± 0.4c 3.3 ± 0.4d
Oxygen saturation bde 85.5 ± 8.8 84.7 ± 9.8 72.2 ± 18.3b 83.4 ± 10.6 68.2 ± 16.7d,e
PaO2/FiO2 bde 256.4 ± 104.4 226.4 ± 88.1 169.6 ± 94.9b 223.1 ± 91.2 151.4 ± 85.6d,e
Estimated glomerular filtration rate abcd 95.4 ± 23.1a 72.8 ± 22.9 59.5 ± 24.9b 57.3 ± 22.1c 48.6 ± 22.4d
Lymphocytes d 956.6 ± 530.2 816 ± 501.3 700.9 ± 443.3 642.2 ± 361.5 547.6 ± 348.2d
Thoracic subcutaneous a. t. ab 23.2 ± 8.4a 14.1 ± 7.9 17.3 ± 9.9b 13.9 ± 8.3 13.4 ± 6.9
TyG-BMI index 155.3 ± 34.5 150 ± 28.5 165.4 ± 36.9 141.6 ± 28.2 146.8 ± 26.4
Body mass index 31 ± 6.4 29.9 ± 5 31.9 ± 6 29 ± 5.2 28.6 ± 4.2
Weight ad 76.9 ± 17a 86.5 ± 16.2 90.6 ± 20 80.3 ± 13.1 77.5 ± 11.2d
Hepatic steatosis c 0.4 ± 0.5 0.4 ± 0.5 0.5 ± 0.5 0.1 ± 0.4c 0.3 ± 0.4
Heart rate ce 101.4 ± 20.1 105.4 ± 15.7 107.3 ± 21.1 92.3 ± 18.8c 105.6 ± 16.1e
Axillary temperature 37.1 ± 0.8 37.3 ± 0.9 37.2 ± 0.9 36.9 ± 0.7 37.2 ± 0.8
Prothrombin a 11.6 ± 1.3a 11.9 ± 1.2 12.3 ± 4.4 14 ± 13.7 14.5 ± 16.2
Vitamin D a 20.4 ± 7.1a 23.7 ± 9.9 20.8 ± 7.4 25.3 ± 9.4 20.3 ± 6.4
Height d 1.6 ± 0.1 1.7 ± 0.1 1.7 ± 0.1 1.7 ± 0.1 1.6 ± 0.1d
Hemoglobin d 16.6 ± 23.5 16.1 ± 1.5 16 ± 1.6 15.8 ± 1.9 15.2 ± 1.6d
Diastolic pressure 74.8 ± 10.4 77.5 ± 10.3 75.8 ± 10.9 74.9 ± 11.2 73.2 ± 12.6
Mean arterial pressure 90.7 ± 10.5 92.8 ± 10.7 90.6 ± 11.7 92.1 ± 11 88.4 ± 14.6
Systolic pressure 122.5 ± 15.1 123.3 ± 15.1 120.1 ± 17.6 126.4 ± 16.2 121.7 ± 17.4
Pulse pressure 47.7 ± 13.2 45.8 ± 12 44.4 ± 14.6 51.5 ± 15 50 ± 18.2
Cytopenia 0.4 ± 0.6 0.4 ± 0.6 0.3 ± 0.5 0.4 ± 0.7 0.3 ± 0.6
Serum creatinine abd 1.2 ± 4.9a 1.1 ± 1.1 1.6 ± 2.7b 1.4 ± 1.4 1.7 ± 2.8d
Consolidation c 0.5 ± 0.5 0.6 ± 0.5 0.5 ± 0.5 0.3 ± 0.5c 0.5 ± 0.5
Grounded glass opacity c 0.5 ± 0.5 0.6 ± 0.5 0.5 ± 0.5 0.3 ± 0.5c 0.5 ± 0.5
Ventilatory support time b 1.7 ± 5 2.6 ± 6.4 4.8 ± 7b 1.5 ± 4.8 2.2 ± 6.1
Hospitalization time 7.6 ± 8.4 9.5 ± 9.6 8.5 ± 6.9 10.1 ± 11.3 7.6 ± 6.7
Platelets 231.1 ± 98.2 230.3 ± 92.2 237 ± 82.8 235.7 ± 90.7 224.8 ± 75.1
Symptomatic time 7.7 ± 4.1 8.1 ± 3.6 8.7 ± 4.3 9.4 ± 5.2 8.9 ± 3.8
Indirect bilirubin a 0.4 ± 0.2a 0.5 ± 0.3 0.5 ± 0.2 0.6 ± 0.3 0.5 ± 0.2
Direct bilirubin a 0.1 ± 0.1a 0.3 ± 0.3 0.3 ± 0.2 0.3 ± 0.6 0.2 ± 0.1
Epicardial fat a 9.9 ± 5.4a 9.2 ± 3 10.4 ± 3.4 10.5 ± 4.3 10.7 ± 3.8
Creatinine kinase a 94.7 ± 92.2a 271.2 ± 420.8 337.6 ± 367.2 226.9 ± 193.4 238.5 ± 237.1
Alanine transaminase a 45.9 ± 87.1a 53.3 ± 41.8 78.9 ± 197 48.8 ± 58.9 57.6 ± 123.5
Aspartate aminotransferase ab 44.8 ± 48.9a 53.2 ± 38.9 128.9 ± 413.6b 68.4 ± 93 77.8 ± 150.2
Ferritin a 428 ± 1227a 895 ± 626 1,355 ± 1,592 906 ± 703 1,130 ± 2,112
Lactic dehydrogenase abde 325 ± 129a 395 ± 185 632 ± 643b 403 ± 140 551 ± 379d,e
Respiratory rate bd 26.6 ± 11.8 26.5 ± 7.6 34.7 ± 11.3b 28.3 ± 10.4 31.2 ± 8d
Pulmonary involvement bde 2 ± 0.8 2.2 ± 0.7 2.7 ± 0.6b 2.3 ± 0.7 2.9 ± 0.3d,e
Fibrinogen a 594.7 ± 175.1a 690.5 ± 196.4 740.3 ± 208 659.4 ± 201.7 779 ± 151
C-reactive protein bde 11.7 ± 8.5 14.9 ± 14.2 30.4 ± 86.7b 16.1 ± 9.7 36.8 ± 94.9d,e
Neutrophils/lymphocytes abd 7.4 ± 7a 10.1 ± 10.5 17.1 ± 17.6b 12.5 ± 11.3 21.5 ± 22.1d
Leukocytes ab 7.4 ± 5.2a 8.7 ± 4.2 11.3 ± 5b 8.1 ± 3.8 11 ± 5.6
Total neutrophils b 5.3 ± 5.3 6 ± 4.3 8.9 ± 5.5b 6.2 ± 4.1 8.4 ± 6.4
Triglycerides 157 ± 71.3 168.4 ± 83.7 179.1 ± 76.9 159.8 ± 77.5 174.9 ± 132.7
TyG index b 4.9 ± 0.3 4.9 ± 0.3 5.2 ± 0.4b 5 ± 0.4 5.1 ± 0.4
Glucose bd 134.3 ± 73.9 136.2 ± 70.8 199 ± 116b 158.6 ± 86.9 217.5 ± 145.2d
Blood urea nitrogen abcd 13 ± 8.4a 16.4 ± 10.5 24.2 ± 21.3b 25.2 ± 20.8c 31.3 ± 17.2d
BUN to creatinine ratio cd 17.2 ± 11.7 15.4 ± 6 17.8 ± 6.9 19.6 ± 6.9c 22 ± 6.9d
D-dimer bd 1,115 ± 2,881 1,654 ± 7,311 3,524 ± 10818b 1,169 ± 1,005 3,325 ± 7071d
Ultrasensitive troponin abcde 7.4 ± 24.4a 29.1 ± 248.5 86 ± 203.7b 77.1 ± 509.1c 93.3 ± 216.4d,e
Age bcd 44.5 ± 9.5 43.5 ± 9.4 48.6 ± 8.2b 66.1 ± 5.6c 67.9 ± 6.6d
Right pulmonary artery abcd 19.9 ± 2.7a 21.2 ± 3.2 23.2 ± 2.6b 23.3 ± 3.3c 24.9 ± 3.4d
Left pulmonary artery bcd 20 ± 2.6 21 ± 2.8 23.1 ± 2.3b 22.8 ± 2.9c 24.1 ± 3.1d
Pulmonary artery trunk b 27.2 ± 3.9 28 ± 3.4 30.7 ± 4b 28.8 ± 5.2 30.1 ± 4.8

Difference between MYR-FYR due to sex in young and recovered (a). Difference between MYR-MYR due to outcome in young men (b). Difference between MYR-MOR due to age in men that recovered (c). Difference between MYR-MOD due to age and outcome in men (d). Difference between MOR-MOD due to outcome in old men (e).