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. 2022 Mar 10;12:840616. doi: 10.3389/fonc.2022.840616

Table 3.

The DALYs and age-standardized DALY Rates of CLL in 1990 and 2013, and the trends from 1990 to 2019.

DALYs (×102, 95% UI) Age-Standardized DALY Rates per 100,000 (95% UI)
1990 2019 Change Percentages of DALYs (%) 1990 2019 EAPCs of Age-Standardized DALY Rates (95% CI)
Global 4,920.74 (4,452.50, 5,322.84) 9,484.64 (8,741.97, 10,652.54) 92.75 12.5 (11.41, 13.48) 11.65 (10.72, 13.1) -0.34 (-0.4, -0.27)
Genders Male 2,620.91 (2,263.04, 2,864.75) 4,858.99 (4,363.26, 5,723.79) 85.39 14.8 (12.86, 16.02) 13.01 (11.68, 15.29) -0.49 (-0.59, -0.39)
Female 2,299.84 (2,055.07, 2,577.62) 4,625.65 (4,120.79, 5,275.03) 101.13 10.77 (9.61, 12.03) 10.63 (9.47, 12.13) -0.19 (-0.26, -0.12)
SDI Quintiles High SDI 1,944.55 (1,776.26, 2,089.29) 2,632.63 (2,353.15, 3,229.85) 35.39 18.53 (16.9, 19.96) 13.64 (12.28, 16.72) -1.32 (-1.5, -1.14)
High-middle SDI 1,402.98 (1,248.66, 1,554.35) 2,545.13 (2,341.45, 2,840.04) 81.41 12.9 (11.5, 14.3) 12.71 (11.69, 14.15) -0.08 (-0.24, 0.08)
Middle SDI 734.69 (597.50, 867.40) 2,033.96 (1,805.27, 2,342.81) 176.84 6.26 (5.22, 7.22) 8.04 (7.12, 9.26) 1.02 (0.91, 1.13)
Low-middle SDI 569.47 (479.14, 679.76) 1,555.53 (1,345.94, 1,816.49) 173.15 9.17 (7.66, 10.92) 11.2 (9.67, 13.08) 0.57 (0.43, 0.71)
Low SDI 266.93 (210.66, 325.61) 713.44 (597.46, 834.46) 167.28 11.24 (8.89, 13.74) 13.88 (11.55, 16.31) 0.75 (0.7, 0.79)
GBD Regions East Asia 520.51 (383.84, 700.76) 1,501.93 (1,249.41, 1,826.59) 188.55 4.7 (3.51, 6.24) 7.75 (6.44, 9.4) 2.19 (1.95, 2.43)
Southeast Asia 95.06 (79.00, 116.84) 290.03 (238.18, 364.78) 205.1 3.61 (3.01, 4.37) 4.87 (3.99, 6.11) 1.01 (0.95, 1.07)
Oceania 0.55 (0.40, 0.73) 1.21 (0.86, 1.70) 121.32 1.45 (1.08, 1.93) 1.36 (0.98, 1.86) -0.44 (-0.51, -0.36)
Central Asia 48.80 (40.69, 55.21) 72.53 (60.94, 88.87) 48.63 9.36 (7.82, 10.62) 9.17 (7.69, 11.13) -0.17 (-0.25, -0.09)
Central Europe 237.03 (213.69, 284.28) 533.43 (453.28, 643.32) 125.05 15.98 (14.42, 18.91) 25.09 (21.23, 30.39) 1.96 (1.53, 2.38)
Eastern Europe 572.17 (457.99, 677.76) 734.59 (642.27, 832.19) 28.39 20.13 (16.1, 23.97) 21.56 (18.85, 24.43) 0.1 (-0.1, 0.3)
High-income Asia Pacific 44.68 (41.66, 54.63) 75.89 (64.80, 93.91) 69.86 2.24 (2.09, 2.73) 1.86 (1.63, 2.21) -0.61 (-0.73, -0.5)
Australasia 48.97 (44.43, 57.37) 85.41 (72.99, 106.85) 74.4 20.68 (18.76, 24.18) 16.77 (14.37, 21.09) -1.05 (-1.24, -0.86)
Western Europe 1,201.95 (1,103.38, 1,289.05) 1,615.22 (1,433.69, 1,939.40) 34.38 20.77 (19.08, 22.32) 17.13 (15.32, 20.79) -0.86 (-1.08, -0.63)
Southern Latin America 44.39 (38.59, 50.01) 67.59 (59.68, 80.02) 52.28 9.63 (8.37, 10.86) 8.05 (7.12, 9.5) -1.03 (-1.31, -0.74)
High-income North America 882.94 (793.23, 938.53) 1,181.33 (1,059.13, 1,444.17) 33.8 24.98 (22.45, 26.54) 18.38 (16.56, 22.54) -1.48 (-1.66, -1.29)
Caribbean 23.04 (20.49, 25.55) 43.37 (36.26, 51.76) 88.27 8.72 (7.79, 9.65) 8.4 (7.02, 10) -0.14 (-0.25, -0.03)
Andean Latin America 8.65 (7.05, 10.96) 30.46 (23.15, 38.63) 251.98 3.68 (3.04, 4.62) 5.3 (4.06, 6.68) 1.5 (1.34, 1.65)
Central Latin America 45.64 (40.66, 48.47) 126.43 (104.93, 155.05) 176.98 5.12 (4.58, 5.44) 5.36 (4.46, 6.57) 0.03 (-0.07, 0.12)
Tropical Latin America 61.89 (56.85, 66.36) 169.91 (152.08, 199.02) 174.56 6.79 (6.24, 7.27) 7.1 (6.35, 8.32) 0.24 (0.17, 0.32)
North Africa and Middle East 154.10 (118.40, 191.88) 393.18 (329.89, 465.10) 155.14 8.15 (6.38, 10.08) 8.82 (7.5, 10.48) 0.19 (0.12, 0.26)
South Asia 638.87 (529.44, 766.80) 1,826.08 (1,549.90, 2,178.30) 185.83 11.4 (9.38, 13.73) 13.01 (11.03, 15.5) 0.25 (0.1, 0.4)
Central Sub-Saharan Africa 15.34 (10.57, 23.11) 68.29 (45.38, 99.00) 345.21 6.5 (4.51, 9.57) 12.68 (8.5, 18.45) 2.66 (2.34, 2.98)
Eastern Sub-Saharan Africa 97.46 (74.45, 124.07) 265.68 (216.60, 332.14) 172.61 13.5 (10.35, 17.06) 17.46 (14.2, 21.77) 0.99 (0.93, 1.05)
Southern Sub-Saharan Africa 84.00 (72.20, 95.27) 170.79 (146.70, 196.15) 103.32 28.73 (24.35, 32.85) 29.73 (25.33, 33.8) 0.38 (0.13, 0.64)
Western Sub-Saharan Africa 94.70 (78.04, 111.70) 231.27 (185.09, 277.07) 144.21 10.78 (8.92, 12.65) 12.63 (10.16, 15) 0.68 (0.63, 0.73)

DALY, disability-adjusted life year; EAPCs, estimated annual percentage changes; SDI, socio-demographic index; CI, confidence interval; UI, uncertainty interval.