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. 2022 Mar 28;5(3):e224750. doi: 10.1001/jamanetworkopen.2022.4750

Table. Demographics, Disease Severity, and Vaccine Reactogenicity.

Demographics Participants, No. (%) (N = 63)
Vaccinated (n = 15) Not vaccinated (n = 48)
Age, mean (range), y 14.4 (12-18) 15.3 (12-21)
Male 10 (67) 27 (56)
Female 5 (33) 21 (44)
BMI, mean (range) 25.1 (18.9-44.8) 26.5 (16.7-48.8)
Racial or ethnic minority groupa 10 (67) 39 (81)
Disease severity
Intensive care 10 (73) 33 (69)
Hypotension 11 (73) 33 (69)
Ionotropic support 5 (33) 27 (56)
Intubation 2 (13) 11 (23)
Received corticosteroids 15 (100) 48 (100)
Received high dose immunoglobulin 11 (73) 34 (71)
Received anakinra 10 (67) 37 (77)
Length of stay, mean (range), d 10.9 (2-33) 11.4 (3-55)
Vaccine reactogenicity (n = 12)b
Local site
Pain 7 (58) NA
Redness 0 NA
Swelling 0 NA
Systemic NA
Fatigue 4 (33) NA
Headache 4 (33) NA
Myalgia 0 NA
Fever 1 (8) NA
Nausea 1 (8) NA

Abbreviations: BMI indicates body mass index, which is calculated as weight in kilograms divided by height in meters squared; NA, not applicable.

a

For this study, racial and ethnic minority groups include Asian patients, Black patients, and Hispanic patients.

b

Three Patients did not directly report.