Skip to main content
. 2022 Mar 10;12:776996. doi: 10.3389/fcimb.2022.776996

Figure 1.

Figure 1

Transcriptional profiling of P. gingivalis in HUVECs. (A) Transcriptional patterns of intracellular P. gingivalis (infection) and P. gingivalis culture in the medium (control) showing clear divergence as determined via PCA. (B) Volcano plot of differentially expressed genes. (C) Bar plots of enriched GO terms of upregulated genes in intracellular P. gingivalis. (D) Detection of the expression levels of livh and livk in P. gingivalis. FC of the expression level of each gene in intracellular P. gingivalis (infection) relative to that in the P. gingivalis culture medium (control). HUVECs, human umbilical vein endothelial cells; PCA, principal component analysis; FC, fold change. The results presented are the average of three independent experiments and are presented as mean ± SD; ****P ≤ 0.0001.