Table 2.
Genotype | rs (reference SNPb cluster ID) | Allele observed (n) | Allele expected (n) | χ2 (df) |
Apoc-E2, E3, E4 |
|
|
|
|
|
7412 | 0=CC (443), 1=CT (83), 2=TT (3) | 0=CC (444), 1=CT (81), 2=TT (4) | 0.14 (2) |
|
429358 | 0=CC (10), 1=CT (127), 2=TT (389) | 0=CC (10), 1=CT (126), 2=TT (389) | 0.01 (2) |
BDNFd Val66Met | 6265 | 0=GG (365), 1=GA (148), 2=AA (15) | 0=GG (365), 1=GA (148), 2=AA (15) | 0.00 (2) |
COMT-1e | 4633 | 0=CC (128), 1=CT (256), 2=TT (144) | 0=CC (124), 1=CT (263), 2=TT (140) | 0.45 (2) |
COMT-2 Val158Met | 4680 | 0=AA (144), 1=AG (256), 2=GG (128) | 0=AA (140), 1=AG (263), 2=GG (124) | 0.45 (2) |
DRD2f | 6277 | 0=CC (112), 1=CT (275), 2=TT (141) | 0=CC (118), 1=CT (263), 2=TT (146) | 1.06 (2) |
DRD1g-48A/G | 4532 | 0=CC (39), 1=CT (129), 2=TT (93) | 0=CC (41), 1=CT (124), 2=TT (95) | 0.27 (2) |
CHRNA6h-1 | 1072003 | 0=CC (346), 1=CG (161), 2=GG (21) | 0=CC (344), 1=CG (163), 2=GG (19) | 0.17 (2) |
CHRNA6-3 | 2304297 | 0=AA (32), 1=AG (200), 2=GG (296) | 0=AA (33), 1=AG (198), 2=GG (297) | 0.05 (2) |
CHRNB3i-1 | 13280604 | 0=AA (311), 1=AG (192), 2=GG (25) | 0=AA (314), 1=AG (186), 2=GG (28) | 0.40 (2) |
CHRNB3-2 | 4950 | 0=AA (311), 1=AG (191), 2=GG (26) | 0=AA (313), 1=AG (187), 2=GG (28) | 0.23 (2) |
GPCPD1j (EDI3) | 6116869 | 0=GG (198), 1=GT (249), 2=TT (79) | 0=GG (198), 1=GT (249), 2=TT (79) | 0.00 (2) |
GRIN2Ak | 1969060 | 0=CC (19), 1=CT (165), 2=TT (342) | 0=CC (19), 1=CT (164), 2=TT (343) | 0.02 (2) |
GRIN2A | 8057394 | 0=GG (285), 1=GC (207), 2=CC (36) | 0=GG (286), 1=GC (205), 2=CC (37) | 0.03 (2) |
GRIN2Bl | 890 | 0=GG (126), 1=TG (254), 2=TT (148) | 0=GG (121), 1=TG (263), 2=TT (143) | 0.69 (2) |
ILm-1beta | 16944 | 0=GG (235), 1=GA (221), 2=AA (70) | 0=GG (227), 1=GA (237), 2=AA (62) | 2.43 (2) |
IL-6 | 1800795 | 0=CC (85), 1=CG (265), 2=GG (176) | 0=CC (90), 1=CG (255), 2=GG (181) | 0.78 (2) |
IL-12A | 568408 | 0=AA (9), 1=AG (141), 2=GG (178) | 0=AA (19), 1=AG (120), 2=GG (188) | 9.53 (2) |
TNF-alphan | 1800629 | 0=AA (15), 1=AG (141), 2=GG (372) | 0=AA (14), 1=AG (143), 2=GG (370) | 0.13 (2) |
aThe chi-square test indicates the conformity between the expected and observed distribution. Significant deviances from the HWE are italicized.
bSNP: single nucleotide polymorphism.
cAPO: apolipoprotein.
dBDNF: brain-derived neurotrophic factor.
eCOMT: catechol-O-methyltransferase.
fDRD2: dopamine receptor D2.
gDRD1: dopamine receptor D1.
hCHRNA6: cholinergic receptor nicotinic alpha 6.
iCHRNB3: cholinergic receptor nicotinic beta 3.
jGPCPD1: glycerophosphocholine phosphodiesterase.
kGRIN2A: glutamate ionotropic receptor NMDA type subunit 2A.
lGRIN2B: glutamate ionotropic receptor NMDA type subunit 2B.
mIL: interleukin.
nTNF-alpha: tumor necrosis factor-alpha.