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. 2022 Mar 3;12:810263. doi: 10.3389/fonc.2022.810263

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Copyright © 2022 Henriksen, del Mar Álvarez-Torres, Figueiredo, Hangel, Keil, Nechifor, Riemer, Schmainda, Warnert, Wiegers and Booth

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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MRI with DCE parameter maps. (A) FLAIR and (B) post-contrast T₁-weighted (T₁+C) images of a patient with a primary brain tumor. In addition, the extended Tofts’ model was used to fit DCE-MRI data to generate parameter maps of (C) K^trans and (D) V_p. (Images are courtesy of Imaging Biometrics LCC).