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. 2022 Mar 21;2022:7507857. doi: 10.1155/2022/7507857

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Copyright © 2022 Weiwei He et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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p53 regulated erastin-induced ferroptosis by SLC7A11/xCT in schwannoma cells. (a) Fluorescence analysis of SLC7A11/xCT between schwannoma cells and schwannoma cells transfected with p53. Relative expression of SLC7A11/xCT decreased significantly in the control and p53-overexpression cells (scale bar: 20 μM). (b) Expression of proteins between the control and overexpression-p53 schwannoma cells. The cell viability was measured with CCK-8 following 24 h erastin treatment in different schwannoma cells.