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. 2022 Mar 21;2022:7507857. doi: 10.1155/2022/7507857

Figure 6.

Figure 6

The inhibition effects of Nutlin-3 and/or erastin schwannoma in vitro. (a) The cell was treat with Nutlin-3 (20 μM), erastin (50 μM), and Nutlin-3 (20 μM) and erastin (50 μM) for 24 hrs. The cell viabilities in the Nutlin-3 group, erastin group, and Nutlin-3 and erastin group (∗∗p < 0.005). The death cells in different groups were evaluated by Annexin V-FITC and PI. (b) The dynamic changes in the HEI-193 schwannomas (left panel) and the tumor-to-body weight ratios (right panel) in different groups. The images of mice and resected tumors (bottom panel) in the endpoint. n = 4.∗p < 0.05.