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. 2022 Jan 30;12(2):234. doi: 10.3390/biom12020234

Figure 2.

Figure 2

The serum from CD1 mice contains greater levels of proinflammatory cytokines than that from C57BL/6 or DBA/2 mice. The number of mice analyzed per experimental group is indicated by n. Since age and sex analyzed as independent variable did not reveal any statistically significant difference, results obtained at different ages in females and males were pooled (see Figure S4 and Tables S2–S4, Supplementary Materials). The number of mice analyzed in each group was: TGF-β1: adult CD1 males n = 5; adult CD1females n = 3, old CD1 males n = 4; old CD1 females n = 3, total CD1 n = 15; adult C57BL/6 males n = 4; adult C57BL/6 females n = 3, old C57BL/6 males n = 5; old C57BL/6 females n = 3, total C57BL/6 n = 15; adult DBA/2 males n = 5; adult DBA/2 females n = 5, old DBA/2 males n = 5; old DBA/2 females n = 5, total DBA/2 n = 20; LCN2: adult CD1 males n = 5; adult CD1 females n = 4, old CD1 males n = 5; old CD1 females n = 5, total CD1 n = 19; adult C57BL/6 males n = 5; adult C57BL/6 females n = 5, old C57BL/6 males n = 5; old C57BL/6 females n = 5, total C57BL/6 n = 20; adult DBA/2 males n = 5; adult DBA/2 females n = 5, old DBA/2 males n = 5, old DBA/2 females n = 5; total DBA/2 n = 20; CXCL1: adult CD1 males n = 8; adult CD1 females n = 6, old CD1 males n = 6; old CD1 females n = 5, total CD1 n = 25; adult C57BL/6 males n = 3; adult C57BL/6 females n = 5, old C57BL/6 males n = 5; old C57BL/6 females n = 5, total C57BL/6 n = 18; adult DBA/2 males n = 5, adult DBA/2 females n = 4, old DBA/2 males n = 5; old DBA/2 females n = 4, total DBA/2 n = 18. P values were calculated with Tukey multiple comparison test and statistically significant differences (p < 0.05) indicated in the panels. Abbreviations: TGF-β1, transforming growth factor β1; LCN2, lipocalin-2.