Table 2.
Comparison of the number of synergic pairs in HT-29 and MCF-7 cell lines treated with the combination of CNS drugs (Drug B) and appropriate references (Drug A).
| Drug A | Drug B | HT-29 * | MCF-7 |
|---|---|---|---|
| Number of Synergic Interactions | Number of Synergic Interactions | ||
| 5-FU | Mefloquine | 1 | N.D. |
| Artesunate | 0 | ||
| Latrepirdine | 1 | ||
| Fluphenazine | 0 | ||
| Fluoxetine | 1 | ||
| Benztropine | 1 | ||
| Thioridazine | 3 | ||
| Sertraline | 5 | ||
| DOX | Artesunate | N.D. | 4 |
| Chloroquine | 3 | ||
| Mefloquine | 1 | ||
| Pyronaridine | 2 | ||
| Tafenoquine | 0 | ||
| Fluoxetine | 1 | ||
| Sertraline | 0 | ||
| Thioridazine | 0 | ||
| Benztropine | 0 | ||
| Fluphenazine | 0 | ||
| PTX * | Artesunate | N.D. | 2 |
| Chloroquine | 2 | ||
| Mefloquine | 1 | ||
| Pyronaridine | 3 | ||
| Tafenoquine | 0 | ||
| Fluoxetine | 3 | ||
| Sertraline | 2 | ||
| Thioridazine | 3 | ||
| Benztropine | 3 | ||
| Fluphenazine | 3 |