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. 2022 Jan 21;12(2):179. doi: 10.3390/biom12020179

Table 1.

Structural features of active zones at the presynaptic terminal.

Synapse Species Age Active Zone Number Per Presynaptic Terminal Presynaptic Terminal Size Active Zone Density Active Zone Size Reference
NMJ Mouse Day 54 780 295 μm2 2.6/μm2 0.082 μm2 [17]
NMJ Mouse Adult 850 335.9 μm2 2.5/μm2 * N.P. [15]
NMJ Human 67 years N.P. 122.7 μm2 N.P. N.P. [18]
NMJ Human Adult N.P. N.P. 2.6/μm2 N.P. [19]
Stratum radiatum in CA1 hippocampus Mouse Adult one for more than 90% of synapses 0.086 μm3 13.4/μm3 * 0.039 μm2 [20]
Piriform cortex layer 1a Mouse 7 months one for more than 90% of synapses 0.367 μm3 3.1/μm3 * 0.095 μm2 [21]
Piriform cortex layer 1b Mouse 7 months one for more than 90% of synapses 0.208 μm3 5.5/μm3 * 0.097 μm2 [21]
Calyx of Held Rats Day 9 554 1022 μm2 0.54/μm2 * N.P. [22]
Calyx of Held Rats Day 14 678 N.P. N.P. 0.089 μm2 [24]

* Calculated from data in the papers. N.P.: not provided.