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. 2022 Jan 21;12(2):175. doi: 10.3390/biom12020175

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Comparing significantly perturbed metabolites (SPMs) of snf3Δ rgt2Δ and ras2Δ. (a) Venn diagram of subsets of SPMs, for snf3Δ rgt2Δ vs. wildtype and ras2Δ vs. wildtype, after glucose addition. The upper semicircle shows up-regulated SPMs and lower semicircle shows down-regulated SPMs. Numbers in parenthesis are shared SPMs regulated in the opposite direction, and are placed in the area corresponding to the direction of regulation. Numbers in parenthesis are shared SPMs regulated in the opposite direction, and are placed in the area corresponding to the direction of regulation. SPMs used for ORA analysis that are (b) shared and change in the same direction; (c) shared and change in the opposite direction. Listed are all pathways and their functional categories with adjusted p-value < 0.05.