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. 2022 Jan 27;12(2):218. doi: 10.3390/biom12020218

Figure 5.

Figure 5

RT–PCR assessment of neuronal gene expression of SCAP treated with ATRA (1 μM) or UDP-4 (1 mΜ). (A) ENO2 expression was significantly upregulated after 96 h of treatment with ATRA or UDP-4. (B) NF1 expression was significantly upregulated after 96 h of treatment with ATRA or UDP-4. (C) CHAT expression was significantly downregulated over the course of treatment with ATRA, while it was significantly upregulated as early as 48 h after treatment with UDP-4. (D) TH expression was not altered by treatment with ATRA, while it was significantly upregulated over the course of treatment with UDP-4. (E) SLC32A1 expression was significantly upregulated over the course of treatment with ATRA, while it was not affected by the UDP-4. ***: p < 0.001, * p < 0.05, n.s.: p > 0.05, and error bars correspond to the standard error of the mean.