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Timeline of myeloproliferative neoplasms. In gray, the clinical era of the MPNs can be seen, which is based on semiological aspects. In orange, the genetic era of MPNs is highlighted, since associated genetic research made it possible to identify genetic alterations that are markers of some MPNs, an important factor that supports diagnosis. CML: chronic myeloid leukemia; BCR/ABL: BCR/ABL genetic rearrangement.
