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Promoters of human and mouse genes coding molecular components of the photoreceptor outer segment (phototransduction cascade) and inner segment are mostly hypermethylated in embryonic retinas/RPCs (the corresponding proteins are marked in red). The genes are colored green for rods, purple for cones, and black indicates expression in both rods and cones. (5mC- 5-methylcytosine, gene with hypermethylated promoter; bivalent-bivalent promoter).
