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. 2022 Mar 11;13:819080. doi: 10.3389/fimmu.2022.819080

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Copyright © 2022 Xiong, Li, Wan, Zheng, Zhang, Wang and Fan

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Characteristics of m6A related phenotypes. (A) DEGs associated with the m6A phenotype. (B) GO enrichment analysis of differential genes (DEGs). (C) KEGG enrichment analysis of differential genes (DEGs). (D) Lasso analysis was used to obtain 41 signature genes of m6A methylation pattern. (E) The expression of common signatures in 2 m6A gene-clusters. (F) The expression of common immune activation genes in the 2 gene-clusters. (G) Abundance of Immune cell abundance in the 2 gene-clusters. *, **, and *** indicate p = < 0.05, < 0.01, and < 0.001, respectively.