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. 2022 Mar 11;13:819080. doi: 10.3389/fimmu.2022.819080

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Copyright © 2022 Xiong, Li, Wan, Zheng, Zhang, Wang and Fan

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Construction of glioblastoma m6A scoring system (GM-score).(A) Alluvial diagram of GBM patient m6A cluster, m6A gene-cluster, and GM-score. (B) GM-score of the two m6A gene clusters. (C) GM-score of the two m6A clusters. (D) Degree of enrichment of stromal activation pathways in 2 GM-score subgroups. (E) Immune cell abundance in the 2 GM-score subgroups. (F) Differences in GM-score between various GBM subtypes. (G) Kaplan-Meier OS analysis of 2 GM-score subgroups in meta_cohort. (H) Kaplan-Meier OS analysis of 2 GM-score subgroups in CGGA cohort. (I) Independent prognostic analysis of GM-score. *, **, and *** indicate p = < 0.05, < 0.01, and < 0.001, respectively.