TABLE 1.
Summary of predictive variables according to CA-AKI in the testing dataset.
| Training dataset |
|||
| Predictive variables | without CA-AKI | CA-AKI | P-value |
| n = 2832 | n = 604 | ||
| Demographic characteristics | |||
| Age, per 10 years | 7 [6, 7] | 7 [7, 8] | <0.001* |
| Male | 1924 (67.9) | 363 (60.1) | <0.001* |
| Diabetes | 653 (23.1) | 163 (27.0) | 0.045* |
| Hypertension | 1766 (62.4) | 387 (64.1) | 0.459 |
| Current smoker | 489 (17.3) | 93 (15.4) | 0.282 |
| Current drinker | 456 (16.1) | 76 (12.6) | 0.030* |
| Abnormal NT-proBNP | 856 (30.2) | 330 (54.6) | <0.001* |
| LVEF <50% | 504 (17.8) | 162 (26.8) | <0.001* |
| MAP ≥90 mmHg | 1094 (38.6) | 153 (25.3) | <0.001* |
| MAP <70 mmHg | 34 (1.2) | 20 (3.3) | <0.001* |
| Prior PCI | 726 (25.6) | 128 (21.2) | 0.022* |
| Prior MI | 221 (7.8) | 45 (7.5) | 0.768 |
| Prior CABG | 46 (1.6) | 14 (2.3) | 0.237 |
| Laboratory testing | |||
| Cardiac troponin I ≥0.02 ng/ml | 962 (34.0) | 362 (59.9) | <0.001* |
| Total cholesterol, mmol/L | 0.031* | ||
| <3.0 | 439 (15.5) | 120 (19.9) | |
| 3.0–5.7 | 2144 (75.7) | 437 (72.4) | |
| >5.7 | 249 (8.8) | 47 (7.8) | |
| C-reactive protein ≥6 mg/L | 755 (26.7) | 255 (42.2) | <0.001* |
| NLR ≥5 | 599 (21.2) | 255 (42.2) | <0.001* |
| Hemoglobin, g/L | <0.001* | ||
| ≥115 | 2392 (84.5) | 408 (67.5) | |
| 90–114 | 381 (13.5) | 147 (24.3) | |
| <90 | 59 (2.1) | 49 (8.1) | |
| HbA1c ≥6.5% | 853 (30.1) | 233 (38.6) | <0.001* |
| eGFR <60 mL/min/1.73 m2 | 480 (16.9) | 149 (24.7) | <0.001* |
| Pre-procedural medication | |||
| Loop diuretics | 763 (26.9) | 325 (53.8) | <0.001* |
| Statins | 2406 (85.0) | 455 (75.3) | <0.001* |
| Angiotensin receptor blockers | 891 (31.5) | 146 (24.2) | <0.001* |
Data are median [interquartile range] or n (%). NT-proBNP indicates N-terminal of the prohormone brain natriuretic peptide; LVEF, left ventricular ejection fraction; MAP, mean arterial pressure; PCI, percutaneous coronary intervention; MI, myocardial infarction; CABG, coronary artery bypass grafting; NLR, neutrophil-to-lymphocyte ratio; eGFR, estimated glomerular filtration rate; CA-AKI, contrast-associated acute kidney injury. *P < 0.05.