TABLE 2.
MICs of β-lactams for C. meningosepticum PINT, E. coli DH10B harboring recombinant plasmid pBS1, and reference strain E. coli DH10B
| β-Lactama | MIC (μg/ml)
|
||
|---|---|---|---|
| C. meningosepticum PINT | E. coli DH10B(pBS1) | E. coli DH10B | |
| Amoxicillin | 256 | 512 | 4 |
| Amoxicillin + CLA | 64 | 4 | 4 |
| Amoxicillin + TZB | 64 | 4 | 2 |
| Amoxicillin + FOX | 128 | 8 | 4 |
| Amoxicillin + MOX | 64 | 16 | 4 |
| Amoxicillin + IPM | 64 | 2 | 4 |
| Ticarcillin | 256 | 512 | 4 |
| Ticarcillin + CLA | 64 | 8 | 4 |
| Ticarcillin + TZB | 128 | 4 | 4 |
| Ticarcillin + FOX | 128 | 32 | 4 |
| Ticarcillin + MOX | 128 | 64 | 4 |
| Ticarcillin + IPM | 128 | 4 | 4 |
| Piperacillin | 32 | 8 | 1 |
| Piperacillin + CLA | 16 | 2 | 1 |
| Piperacillin + TZB | 16 | 2 | 1 |
| Piperacillin + FOX | 16 | 2 | 1 |
| Piperacillin + MOX | 32 | 2 | 1 |
| Piperacillin + IPM | 32 | 2 | 1 |
| Cephalothin | 512 | 256 | 2 |
| Cefoxitin | 32 | 4 | 1 |
| Ceftazidime | 256 | 32 | 0.5 |
| Ceftazidime + CLA | 16 | 0.5 | 0.5 |
| Ceftazidime + TZB | 16 | 0.25 | 0.5 |
| Ceftazidime + FOX | 16 | 1 | 0.5 |
| Ceftazidime + MOX | 64 | 2 | 0.5 |
| Ceftazidime + IPM | 64 | 0.5 | 0.5 |
| Cefotaxime | 64 | 4 | 0.12 |
| Cefepime | 32 | 0.5 | 0.03 |
| Cefepime + CLA | 4 | 0.03 | 0.03 |
| Cefepime + TZB | 4 | 0.03 | 0.03 |
| Cefepime + FOX | 8 | 0.06 | 0.03 |
| Cefepime + MOX | 16 | 0.06 | 0.03 |
| Cefepime + IPM | 16 | 0.06 | 0.03 |
| Aztreonam | >512 | 16 | 0.25 |
| Aztreonam + CLA | >512 | 0.12 | 0.25 |
| Aztreonam + TZB | >512 | 0.25 | 0.25 |
| Aztreonam + FOX | >512 | 0.25 | 0.25 |
| Aztreonam + MOX | >512 | 0.5 | 0.25 |
| Aztreonam + IPM | >512 | 0.25 | 0.25 |
| Moxalactam | 64 | 0.25 | 0.12 |
| Imipenem | 32 | 0.25 | 0.12 |
a
CLA, clavulanic acid at a fixed concentration of 2 μg/ml; TZB, tazobactam at a fixed concentration of 4 μg/ml; FOX, cefoxitin at a fixed concentration of 0.1 μg/ml; IPM, imipenem at a fixed concentration of 0.5 μg/ml; MOX, moxalactam at a fixed concentration of 0.05 μg/ml.