Table 5.

Longitudinal multilevel analysis testing the impact of development status on the incidence and mortality from liver cancer, 1990-2019

Metric	Parameter		Estimate	SE	P value
Incidence	Intercept		5.67	0.78	0.007*
	Time		0.02	0.004	0.025*
	Development status
		More Developed	-1.36	0.22	0.012*
		Less-Developed	Reference	-	-
	Development status × time		0.02	0.01	0.157**
	Random effects
		${\sigma }_{u_{0i}}^2$ (between countries)	63.28	6.84	0.002*
		${\sigma }_{\upsilon 0}^2$ (between regions)	3.96	3.44	0.283**
		${\sigma }_{\omega 0}^2$ (between super-regions)	0.10	0.08	0.262**
	ICC (%)
	Country level	88.2	-	-	-
	Region level	5.5	-	-	-
	Super-region level	0.13	-	-	-
Mortality	Intercept		5.80	0.81	0.007*
	Time		0.02	0.005	0.043*
	Development status
		More Developed	-1.07	0.25	0.038*
		Less-Developed	Reference
	Development status × time		0.03	0.01	0.083**
	Random effects
		${\sigma }_{u_{0i}}^2$ (between countries)	69.93	7.57	0.002*
		${\sigma }_{\upsilon 0}^2$ (between regions)	4.01	3.66	0.296**
		${\sigma }_{\omega 0}^2$ (between super-regions)	0.11	0.10	0.294**
	ICC (%)
	Country level	88.07	-	-	-
	Region level	5.06	-	-	-
	Super-region level	0.14	-	-	-

ICC Intraclass Correlation Coefficient; SE Standard Error, ^*p < 0.05, ^**p > 0.05