Table 1.
The Clinicopathological characteristics of patients with RES after ESD and univariate analysis of endoscopic treatment success
| Category | N (%)/M (range) | Success no | P& | |
|---|---|---|---|---|
| Sex | Female | 27 (54) | 14 | 0.203 |
| Male | 23 (46) | 16 | ||
| Age (years) | – | 65.5 (45–77) | - | 0.921 |
| Smoking history | – | 13 (26) | 9 | 0.430 |
| Drinking history | – | 12 (24) | 7 | 0.892 |
| Depth of in infiltration | m1 | 20 (40) | 16 | 0.200 |
| m2 | 14 (28) | 6 | ||
| m3 | 12 (24) | 6 | ||
| sm1 | 2 (4) | 1 | ||
| sm2 | 2 (4) | 1 | ||
| Tumor location* | Cervical | 31 (62) | 18 | 0.721 |
| Thoracic | 19 (38) | 12 | ||
| Postoperative pathology | HGIN | 20 (40) | 12 | 0.322 |
| SCC | 30 (60) | 18 | ||
| Length of lesion (cm) | – | 9 (2–19) | - | 0.652 |
| Circumferential ratio | 1/2–1 | 18 (36) | 13 | 0.122 |
| 1 | 32 (64) | 17 | ||
| Operating time (min) | – | 102 (40–261) | – | 0.318 |
| En bloc Resection | – | 50 (100) | 30 | - |
| Muscular injury | – | 21 (42) | 14 | 0.413 |
| Clip | – | 4 (8) | 2 | 0.670 |
| Coagulation | – | 24 (48) | 19 | 0.008 |
| Dilation times | – | 6 (3–33) | – | 0.763 |
| Length of strictures (cm) | – | 4 (1–9) | – | 0.643 |
| Number of strictures | One | 43 (86) | 23 | 0.020 |
| Two or more | 7 (14) | 7 | ||
| R0 resection | – | 34 (50) | 20 | 0.558 |
| Dysphagia-free period (days) | – | 42 (7–863) | – | 0.550 |
| Pre-dilation period (days) | – | 51 (9–276) | – | 0.001 |
| Therapy | Dilation + Oral Prednisone | 27 (54) | 10 | < 0.001 |
| Dilation only | 23 (46) | 20 | ||
| Bougie dilator | 11 (22) | 20 | 0.022 | |
| Balloon dilator only | 39 (78) | 10 | ||
| Stents | 7 (14) | 5 | 0.506 | |
| Pre-dilation dysphagia score | – | 4 (1–4) | – | 0.098 |
| Post-dilation dysphagia score | – | 1 (0–4) | – | < 0.001 |
RES: Refractory esophageal strictures
*The location of oral-lateral lesion
&P indicates a significant relationship between characteristics of patients and endoscopic therapy successes in univariate analysis