Table 1.
Clinical characteristics of 160 patients with urolith associated with obstructive urosepsis
| Variable | Sepsis group | Severe sepsis group | Septic shock group | Pvalue |
|---|---|---|---|---|
| Gender (n, %) | ||||
|
Male Female |
22 (22.2) 77 (77.8) |
34 (69.4) 15 (30.6) |
4 (33.3) 8 (66.7) |
0.206 |
| Age(years) | 55.38 ± 15.45 | 65.04 ± 12.88 | 71.83 ± 11.27 | 0.000 |
| BMI (kg/m2) | 24.01 ± 3.55 | 24.69 ± 4.69 | 23.45 ± 3.14 | 0.599 |
| History of diabetes(n, %) | ||||
|
Yes No |
15 (15.2) 84 (84.8) |
12 (24.5) 37 (75.5) |
7 (58.3) 5 (41.7) |
0.003 |
| History of CKI (n, %) | ||||
|
Yes No |
17 (17.2) 82 (82.8) |
18 (36.7) 31 (63.3) |
6 (50.0) 6 (50.0) |
0.001 |
| History of anemia (n, %) | ||||
|
Yes No |
15 (15.2) 84 (84.8) |
12 (24.5) 37 (75.5) |
3 (25.0) 9 (75.0) |
0.148 |
| History of hypertension (n, %) | ||||
|
Yes No |
39(39.4) 60(60.6) |
25(51.0) 24(49.0) |
5(41.7) 7(58.3) |
0.282 |
| History of heart disease(n, %) | ||||
|
Yes No |
2(2.0) 97(98.0) |
7(14.3) 42(85.7) |
2(16.7) 10(83.3) |
0.129 |
| History of cancer (n, %) | ||||
|
Yes No |
4(4.0) 95(96.0) |
3(6.1) 46(93.9) |
0(0.0) 12(100.0) |
0.657 |
| History of urolithiasis surgery (n, %) | ||||
|
Yes No |
28(28.3) 71(71.7) |
17(34.7) 32(65.3) |
1(8.3) 11(91.7) |
0.860 |
| Time interval from ED to admission (h) | 8.78 ± 11.92 | 10.29 ± 11.26 | 13.92 ± 12.63 | 0.038 |
| Highest temperature level (°C) | 39.05 ± 0.57 | 39.18 ± 0.74 | 39.29 ± 0.62 | 0.130 |
| Surface area of stones (cm2) | 0.79 ± 1.47 | 0.51 ± 0.41 | 0.45 ± 0.45 | 0.102 |
| Laterality of stones (n, %) | ||||
|
Left Right |
37 (37.4) 62 (62.6) |
28 (57.1) 21 (42.9) |
3(25.0) 9 (75.0) |
0.213 |
| Location of stones (n, %) | ||||
|
Upper Middle Lower |
54 (54.5) 14 (14.1) 31 (31.3) |
30 (61.2) 3(6.1) 16(32.7) |
4(33.3) 2 (16.7) 6 (50.0) |
0.537 |
| Degree of hydronephrosis (n, %) | ||||
|
Mild Moderate Severe |
63 (63.6) 24 (24.2) 12 (12.1) |
27 (55.1) 15 (30.6) 7 (14.3) |
9 (75.0) 3 (25.0) 0 (0) |
0.823 |
| WBC count (/L) | 18.09 ± 5.93 | 17.97 ± 8.58 | 19.11 ± 8.45 | 0.857 |
| NLR (%) | 18.39 ± 12.63 | 25.74 ± 22.20 | 31.52 ± 30.32 | 0.005 |
| Platelet count (109/L) | 228.18 ± 73.98 | 150.73 ± 89.07 | 113.50 ± 99.97 | 0.000 |
| HBG (g/L) | 121.33 ± 16.92 | 114.04 ± 18.96 | 104.42 ± 16.27 | 0.101 |
| ALB (g/L) | 138.94 ± 4.94 | 34.18 ± 5.26 | 32.60 ± 5.99 | 0.000 |
| SCr (μmol/L) | 103.15 ± 29.80 | 248.08 ± 130.71 | 498.08 ± 660.27 | 0.000 |
| TBil (μmol/L) | 13.58 ± 6.59 | 18.38 ± 18.10 | 29.61 ± 39.69 | 0.004 |
| PT (s) | 12.77 ± 1.19 | 13.47 ± 1.48 | 15.32 ± 3.33 | 0.000 |
| APTT (s) | 28.83 ± 4.51 | 30.42 ± 5.32 | 39.96 ± 14.75 | 0.000 |
| INR (R) | 1.09 ± 0.11 | 1.17 ± 1.38 | 1.33 ± 0.29 | 0.000 |
| CRP (mg/L) | 120.64 ± 76.38 | 156.25 ± 115.68 | 216.89 ± 108.08 | 0.148 |
| PCT (ng/mL) | 13.51 ± 22.50 | 40.40 ± 38.57 | 62.94 ± 45.28 | 0.000 |
| Positive rate of pathogens in urine culture (n, %) | 38(40.9) | 19(38.8) | 6(50.0) | 0.373 |
| Positive rate of urinary nitrite (n, %) | 18(29.5) | 16(32.7) | 16(32.7) | 0.665 |
| Urinary leukocyte count (/ul) | 2499.50 ± 8818.60 | 1600.55 ± 6501.60 | 3789.90 ± 7121.70 | 0.828 |
| Positive rate of pathogens in blood culture (n, %) | 11(22.4) | 9(36.0) | 7(63.6) | 0.001 |