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. 2022 Mar 11;13:841126. doi: 10.3389/fimmu.2022.841126

Figure 1.

Figure 1

Autoantibodies against known autoantigens in adults with COVID-19 not receiving IVIG. Autoantibody levels against eight well known autoantigens (panels A–H) were determined in adults with COVID-19 having varying levels of disease severity: critical, severe, moderate, and mild. Each symbol represents a sample from an individual control subject (SARS-CoV-2 uninfected health care worker (NIH HCW), a patient with COVID-19 (critical, severe, or moderate, or mild). Autoantibody levels are plotted in light units on a log10-scale and the solid horizontal line represents the mean value in each group. The dashed lines represent the cut-off level for determining seropositive autoantibodies as described in the Methods. Only statistically significant P values from the Fisher exact test examining autoantibody prevalence differences between the uninfected HCW and the different severity groups of COVID-19 adults are shown.