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. 2022 Mar 26;27:30. doi: 10.1186/s11658-022-00328-6

Table 1.

Characteristics of participants and rats in control (con) and diabetic nephropathy (DN) groups

Variable Con DN p-Value
Human
Male (%) 53% 70% 0.7160
Age (years) 52.38 ± 15.06 53.82 ± 9.23 0.7475
BMI (kg/m2) 25.34 ± 2.96 24.61 ± 2.65 0.4789
SBP (mmHg) 140.8 ± 17.68 148.1 ± 23 0.3362
DBP (mmHg) 77.5 ± 8.94 80.56 ± 14.79 0.4978
FBG (mmol/L) 5.42 ± 1.19 10.43 ± 5.14  < 0.001
CREA (umol/L) 88.76 ± 32.45 193.7 ± 105.3  < 0.001
CCr (mL/min) 103.1 ± 31.04 54.75 ± 25.93  < 0.0001
24hUTP (mg) 353.8 ± 134.58 2415 ± 1662.56  < 0.0001
UA (umol/L) 309.9 ± 76.07 421.1 ± 42.58  < 0.0001
TP (g/L) 72.3 ± 8.51 60.5 ± 7.83  < 0.0001
Rats
FBG (mmol/L) 5.5 ± 0.6 23.6 ± 4.2  < 0.0001
CREA (umol/L) 21.4 ± 4.3 45.6 ± 9.7  < 0.0001
BUN (mmol/L) 2.5 ± 0.5 6.8 ± 0.9  < 0.0001
24hUTP (mg) 45.6 ± 6.1 320.5 ± 68.3  < 0.0001

Data presented as mean ± SD. BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; FBG, fasting blood glucose; CREA, creatinine; CCr, creatinine clearance; 24hUTP, 24-h urinary protein quantity; UA, uric acid; TP, total protein; BUN, blood urea nitrogen