Figure 5.

Immune cells in abdominal aortic aneurysms. (A) Relative mRNA levels from aneurysmal wall samples from vehicle and CAG treated group of common lymphocyte marker CD45 (n = 9/9), and (B) macrophage/monocyte marker F4-80 (n = 10/10). All RNA data were normalized to RPL41 mRNA levels. (C) Semi-quantification of aneurysmal CD68 positive cells in AAA of each group per mm² in the adventitial layer (n = 8/7). (D) Representative micrographs of CD68 positive cells in vehicle and CAG AAAs on day 28 (enlargement represents black square on the left image). Arrows mark positive cells (n = 8/7). Scale bar (black box) in micrographs to the left: 100 μm and in micrographs to the left: 50 μm. Values are median ± interquartile range.