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. 2022 Feb 18;10(2):490. doi: 10.3390/biomedicines10020490
AE Allotopic expression
AHSCT Allogeneic hematopoietic stem cell transplantation
ALS Amyotrophic lateral sclerosis
ATP Adenosine triphosphate
ETC Electron transport chain
HR Homologous region
HSP Hereditary spastic paraplegias
IMS Intermembrane space
iPSCs Induced pluripotent stem cells
AAV/AAV2 Adeno-associated virus (vector)
NADH Nicotinamide adenine dinucleotide dehydrogenase
LHON Leber’s hereditary optic neuropathy
NARP Neuropathy, ataxia, and retinitis pigmentosa
MELAS Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes
MERRF Myoclonic epilepsy with ragged-red fibers
MIDD Maternally inherited diabetes and deafness
MILS Maternally inherited Leigh syndrome
MIM/IM Mitochondrial inner membrane
MNGIE Mitochondrial neurogastrointestinal encephalomyopathy
mtDNA Mitochondrial DNA
MTS Mitochondrial targeting sequence
OXPHOS Oxidative phosphorylation
RC Respiratory complex
RNS Reactive nitrogen species
ROS Reactive oxygen species
SCA Spinocerebellar ataxias
TALENS Transcription activator-like effector nucleases
TM Transmembrane domain
UTR Untranslated regions