Table 1.
Hyperfiltration is an early event in several kidney diseases.
| Pathophysiology Associated with Hyperfiltration/Kidney Disease | References |
|---|---|
| High dietary protein consumption by vulnerable groups | [18,19,20] |
| Obesity | [21,22,23,24,25,26,27,28,29] |
| Diabetes | [30,31,32,33,34,35,36,37,38,39,40,41,42,43,44] |
| Hypertension | [45,46,47,48,49,50,51,52] |
| Primary hyperaldosteronism | [53,54,55,56] |
| Non-alcoholic fatty liver disease (NAFLD) | [57,58,59,60,61,62] |
| CKD in Kidney donors | [14,17,63,64,65,66,67,68] |
| CKD in Children born with single functioning kidney or low number of functional nephrons due to other Congenital Anomalies of the Kidney and Urinary Tract (CAKUT) | [16,69,70,71,72,73] |
| Autosomal Dominant Polycystic Kidney Disease (ADPKD) | [74] |
| Secondary focal segmental glomerulosclerosis (FSGS) | [75,76,77,78] |
| Sickle cell Disease (SCD) and glomerular sclerosis | [79,80,81,82] |
| Cyanotic congenital heart disease/critical congenital heart disease (CCHD) | [83,84,85,86,87] |
| ‘Autoimmune activation’ and inflammation | [88,89] |
| High altitude renal syndrome | [90] |
| Dementia | [91] |
| Stroke | [92,93] |