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. 2022 Feb 6;10(2):390. doi: 10.3390/biomedicines10020390

Figure 7.

Figure 7

Our hypothesis of the possible mechanism of the increased rate of placenta accreta spectrum disorder. The red arrow indicates the effect of endometriosis on the increased rate of PASD. The light blue arrow indicates the effect of assisted reproductive technology (ART) on the increased rate of PASD. (A) For women with endometriosis who conceived without ART, endometriosis itself may be associated with an increased rate of PASD. Because endometriosis is associated with an increased rate of placenta previa, this may indirectly contribute to a higher rate of PASD. (B) For women with endometriosis who conceived using ART, ART may have an additive effect that increased the rate of placenta previa and PASD. As a result, we believe that women with endometriosis who conceived using ART are at a high risk for PASD. Abbreviations: PP, placenta previa; PASD, placenta accreta spectrum disorder, ART, assisted reproductive technology.