Figure 1.

Flow diagram of recruitment. Patients who dropped out during the treatment or failed to receive at least four cycles of weekly cisplatin (40 mg/m²) concurrently with planned radiotherapy (64–72 Gy) were considered as the incomplete CCRT subgroup. Patients who did not complete required DXA examinations or missed scheduled blood tests were considered as the incomplete data subgroup. LAHNC, locally advanced head and neck cancer; DXA, dual-energy X-ray absorptiometry; CCRT, concurrent chemoradiotherapy.