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. 2022 Feb 6;10(2):388. doi: 10.3390/biomedicines10020388

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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(a–c) Two-year mortality rates of patients with OCC with postoperative adjuvant CCRT stratified by ECOG PS (performance status), PLR, and OCC Factor 3 (change in body muscle mass during CCRT); (d–f) two-year mortality rates of patients with NOCC with primary CCRT stratified by age, NLR, and NOCC Factor 2 (body fat mass before CCRT). OCC, oral cavity cancer; NOCC, non-oral cavity cancer; NLR, neutrophil-to-lymphocyte ratio; PLR, platelet-to-lymphocyte ratio. The cutoff value analyzed by ROC curves for PLR was 197.6 (area under the curve (AUC): 0.807, p < 0.001), that of OCC Factor 3 was 0.049 (AUC: 0.692, p = 0.01), that of age was 52.5 (AUC: 0.708, p = 0.017), that of NLR was 2.73 (AUC: 0.689, p = 0.037), and that of NOCC Factor 2 was 0.30 (AUC: 0.676, p = 0.046).