Table 1.
Closure group | Non-closure group | ||
---|---|---|---|
(97 lesions in 97 patients) | (122 lesions in 122 patients) | P value | |
Patients | |||
Age, mean ± SD (range), years | 69.8 ± 10.7 (42–89) | 69.7 ± 11.3 (39–88) | 0.962 |
Sex, male/female | 64/33 | 74/48 | 0.418 |
Antithrombotic agents, n (%) | 25(26%) | 18 (15%) | 0.041 |
Lesions | |||
Location (colon/rectum) | 85/12 | 84/38 | 0.001 |
Morphology (0–I/0–IIa) | 21/76 | 14/108 | 0.041 |
Histology (adenoma/M/SM1/SM2 or more/other) | 32/48/8/8/1 | 28/67/10/9/8 | 0.388 |
Specimen size, mean ± SD (range), mm | 40.1 ± 12.1 (18–92) | 47.7 ± 16.1 (25–101) | < 0.001 |
Tumor size, mean ± SD (range), mm | 26.8 ± 11.3 (10–87) | 34.8 ± 16.6 (10–92) | < 0.001 |
Simultaneous removal of other polyps*, n (%) | 3 (3%) | 5 (4%) | 1.000 |
ESD outcomes | |||
Procedure time of ESD, mean ± SD (range), min | 61.0 ± 29.0 (12–171) | 85.3 ± 48.7 (11–274) | < 0.001 |
En bloc resection rate (%) | 100 | 98 | 1.000 |
Perforation during ESD, n (%) | 3 (3%) | 1 (1%) | 0.324 |
Outcomes of prophylactic clip closure | |||
Procedure time, mean ± SD (range), min Number of clips, mean ± SD (range) |
12.4 ± 5.2 (4.0–25.0) 9.8 ± 3.2 (3–21) |
– – |
SD: standard deviation
ESD: endoscopic submucosal dissection
*Endoscopic mucosal resection or polypectomy performed for concomitant lesions