eTable 4. Numbers of potentially inappropriate medications and undesirable drug–drug interactions at T0 und T1 by study arm and study center (969 patients).
| PIM: n (%) | DDI: n (%) | ||||||
| Both | Study center | Both | Study center | ||||
| Time | HMS | WHU | HMS | WHU | |||
| All | T0 | 302 | 173 (57.2) | 129 (42.7) | 241 | 138 (57.2) | 103 (42.7) |
| T1 | 305 | 189 (62.0) | 116 (38.0) | 213 | 110 (51.6) | 103 (48.4) | |
| Study arm | |||||||
| Intervention 1 (physician) |
T0 | 82 | 41 (50.0) | 41 (50.0) | 67 | 37 (55.2) | 30 (44.8) |
| T1 | 79 | 42 (53.2) | 37 (46.8) | 64 | 30 (46.9) | 34 (53.1) | |
| Intervention 2 (practice team) |
T0 | 83 | 53 (63.9) | 30 (36.1) | 67 | 40 (59.7) | 27 (40.3) |
| T1 | 81 | 57 (70.4) | 24 (29.6) | 55 | 27 (49.1) | 28 (50.9) | |
| Control | T0 | 137 | 79 (57.7) | 58 (42.3) | 107 | 61 (57.0) | 46 (43.0) |
| T1 | 145 | 90 (62.1) | 55 (37.9) | 94 | 53 (56.4) | 41 (43.6) | |
DDI, undesirable drug–drug interaction; HMS, Hannover Medical School; PIM, potentially inappropriate medication; T0, start of study; T1, end of study; WHU, Witten/Herdecke University