Table 1.
Demographic and clinical characteristics of recipients and donors
| Variables | Total number (n = 251) |
|---|---|
| Recipient age (y), median | 28 (2–63) |
| Children (≤ 16) | 70 (27.9%) |
| Adults (> 16) | 181 (72.1%) |
| Male sex, n (%) | 140 (55.8%) |
| Underling disease (%) | |
| AML | 102 (40.6%) |
| ALL | 99 (39.4%) |
| AA | 20 (8.0%) |
| MDS | 19 (7.6%) |
| Others | 11 (4.4%) |
| Donor age (y), median | 36 (4–64) |
| Male donor sex, n (%) | 190 (75.7%) |
| Donor–recipient ABO blood type | |
| Match, n (%) | 138 (55.0%) |
| Major mismatch, n (%) | 53 (21.1%) |
| Minor mismatch, n (%) | 60 (23.9%) |
| Mononuclear cells (× 108/kg) | 8.74 (6.16–13.97) |
| CD34+ cells (× 106/kg) | 2.76 (0.68–6.03) |
| IFD prophylaxis | |
| Fluconazole | 9 (3.6%) |
| Itraconazole | 181 (72.1%) |
| Voriconazole | 53 (21.1%) |
| Caspofungin | 8 (3.2%) |
AML acute myeloid leukemia, ALL acute lympphocytic leukemia, AA aplastic anemia, MDS myelodysplastic syndrome, IFD invasive fungal disease