Table 3.
Bivariate and multivariate correlation of demographics, anatomical features, and flow dynamics and biomechanics in the false lumen with aortic growth rate
Bivariate | Multivariate | ||||
---|---|---|---|---|---|
R | P-value | Beta | P-value | 95% CI | |
Demographics and clinical data | |||||
Age [years] | 0.018 | 0.899 | |||
Sex (male) | 0.398 | ||||
Body surface area | 0.101 | 0.494 | |||
Systolic blood pressure [mmHg] | 0.086 | 0.566 | |||
Diastolic blood pressure [mmHg] | 0.071 | 0.637 | |||
Smoking | 0.390 | ||||
Hypertension | 0.386 | ||||
Diabetes mellitus | 0.391 | ||||
Dyslipidaemia | 0.396 | ||||
Mechanical prosthetic aortic valve | 0.397 | ||||
Anticoagulation therapy | 0.396 | ||||
Antiplatelet therapy | 0.394 | ||||
Statin therapy | 0.394 | ||||
Type of aortic dissection | 0.481 | ||||
Anatomical features | |||||
Maximum DAo diameter [mm] | 0.280 | 0.042 | |||
Dominant entry tear area [cm2] | 0.257 | 0.096 | 0.371 | 0.018 | [0.130; 1.251] |
Local distance of the dominant entry tear [mm] | -0.094 | 0.513 | |||
Thrombus in the false lumen [%] | 0.336 | 0.037 | 0.293 | 0.049 | [0.000; 0.065] |
Flow dynamics in the false lumen | |||||
Retrograde systolic flow [mL] | 0.165 | 0.237 | |||
Retrograde diastolic flow [mL] | 0.102 | 0.465 | |||
Retrograde flow fraction [%] | 0.060 | 0.708 | |||
IRF [cm2/s] | 0.393 | 0.006 | 0.433 | 0.008 | [0.034; 0.202] |
WSS [N/m2] | 0.279 | 0.060 | |||
KE [mJ] | 0.015 | 0.919 | |||
MSDR [cm/s3] | -0.214 | 0.136 | |||
Flow stasis [%] | 0.106 | 0.457 | |||
Biomechanics in the false lumen | |||||
PWV [m/s] | 0.370 | 0.017 | 0.360 | 0.017 | [0.031; 0.281] |
DAo descending aorta, IRF in-plane rotational flow, KE kinetic energy, MSDR maximum systolic deceleration rate, PWV pulse wave velocity, WSS wall shear stress