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Diagnostic values of the IL-6 methylation level and the combined determination with AFP for distinguishing HBV-associated HCC from CHB.
| Parameter | sensitivity | Specificity | Youden index | AUC | 95%CI |
|---|---|---|---|---|---|
| IL-6 | 78.2 | 72.1 | 0.503 | 0.773 | 0.721-0.819 |
| AFP | 55.6 | 80.6 | 0.362 | 0.686 | 0.630-0.738 |
| IL-6+AFP | 78.2 | 73.3 | 0.515 | 0.784 | 0.732-0.829 |
