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. 2021 Dec 16;14(1):mjab079. doi: 10.1093/jmcb/mjab079

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© The Author(s) (2021). Published by Oxford University Press on behalf of Journal of Molecular Cell Biology, CEMCS, CAS.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Expression and localization of LRRK2 in mouse oocyte meiosis. (A) The expression level of LRRK2 at different stages (GV, GVBD, MI, and MII) was examined by western blotting in mouse oocytes. (B) The localization of LRRK2 was certificated by LRRK2 antibody in mouse oocytes. LRRK2 dispersed in the cytoplasm at the GV stage and was mainly distributed around the spindle after GVBD. Red, LRRK2; blue, DNA; scale bar, 20 μm. (C) LRRK2 was colocalized with actin around the spindle in the MI-stage oocytes. Red, actin; green, LRRK2; blue, DNA; scale bar, 20 μm.