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. 2022 Mar 11;9:819274. doi: 10.3389/fcvm.2022.819274

Table 3.

Hypertension status stratified analyses of abnormal lipid indices and the risk of IS.

Lipid indices Group Non-hypertension Hypertension Pheterogeneityb
HR (95% CI)a P a HR (95% CI)a P a
TC <240 mg/dl reference - reference -
≥240 mg/dl 0.445 (0.176–1.123) 0.086 1.224 (0.801–1.868) 0.350 0.052
TG <200 mg/dl reference - reference -
≥200 mg/dl 0.714 (0.373–1.368) 0.310 1.254 (0.891–1.765) 0.194 0.133
HDL-C 40–60mg/dl reference - reference -
<40 mg/dl 0.884 (0.477–1.639) 0.695 1.157 (0.778–1.720) 0.471 0.472
>60 mg/dl 1.411 (0.883–2.253) 0.150 0.665 (0.450–0.983) 0.041 0.016
LDL-C <160 mg/dl reference - reference -
≥160 mg/dl 0.401 (0.056–2.880) 0.364 1.000 (0.542–1.847) 0.999 0.385
Non-HDL-C <190 mg/dl reference - reference -
≥190 mg/dl 0.319 (0.098–1.036) 0.057 1.565 (1.007–2.429) 0.046 0.013
RC <30 mg/dl reference - reference -
≥30 mg/dl 0.749 (0.488–1.148) 0.184 1.071 (0.795–1.442) 0.651 0.179
TC/HDL-C <3.6 reference - reference -
≥3.6 0.479 (0.307–0.750) 0.001 1.303 (0.955–1.778) 0.094 <0.001
TG/HDL-C <1 reference - reference -
≥1 0.698 (0.447–1.090) 0.114 1.259 (0.925–1.714) 0.143 0.033
LDL-C/HDL-C <2 reference - reference -
≥2 0.800 (0.523–1.223) 0.302 1.414 (1.034–1.933) 0.030 0.126

TC, total cholesterol; TG, triglycerides; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; Non-HDL-C, non-high-density lipoprotein cholesterol; RC, remnant cholesterol.

a

: Adjusted for age, gender, BMI, cigarette smoking, alcohol consumption, T2DM at baseline, and use of lipid-lowering drugs.

b: Pheterogeneity stands for the P value of the heterogeneity test.