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IC50 values for dihydroartemisinin for an artemisinin-susceptible, K13 WT Plasmodium falciparum strain (NF54) and in 4 P. falciparum patient isolates from Rwanda with K13 mutations. Indicated error bars display the mean + SE. p values were determined by Student t-test. IC50, 50% inhibitory concentration; K13, kelch 13; WT, wild-type.
